Yohimbine is an herbal dietary supplement made from the bark of the Pausinystalia and Corynanthe yohimbe trees found in parts of central and western Africa. Yohimbe is used as a remedy for impotence, athletic performance, weight loss, chest pain, high blood pressure, diabetic, plasma testosterone levels, promotes skeletal muscle hypertrophy, sexual vigor, and decreased body fat neuropathy, and more. Yohimbine hydrochloride, which is a standardized form of yohimbine, is also available in the United States as a prescription drug for erectile dysfunction. Yohimbe contains a chemical called yohimbine, which can increase blood flow and nerve impulses to the penis or vagina. It also helps counteract the sexual side effects of certain medications used for depression. Yohimbe has been linked to a number of severe side effects that include irregular or rapid heartbeat, kidney failure, seizure, heart attack, stomach upset, excitation, tremor, sleep problems, anxiety or agitation, high blood pressure, headache, frequent urination, bloating, rash, nausea, dizziness, drooling, sinus pain, irritability, vomiting and others. It should also be noted when taking high doses you can also have severe problems that include difficulty breathing, paralysis, very low blood pressure, heart problems, and even death. If you have prostate problems you should use yohimbe with caution. Yohimbe could make the symptoms of BPH (benign prostatic hyperplasia) worse. If you’re taking a blood thinner talk to your doctor. Yohimbe could increase the risk of bleeding. If you have diabetes and take insulin, Yohimbe could interfere with your insulin and other medications used to treat your diabetes. It can also cause low blood sugar. Don’t use yohimbe if you have high blood pressure or low blood pressure. Small amounts of yohimbine can increase blood pressure. Large amounts can cause dangerously low pressure.